Donkey Secondary Antibodies
ABBERIOR INSTRUMENTS AMERICA LLC STAR ORNG DONKEY ANTI-HU 500UL
NC3370466 STAR ORNG DONKEY ANTI-HU 500UL
Abcam Donkey Fab'2 Anti-Rabbit IgG H&L Alexa Fluor 594 preadsorbed
Donkey Fab'2 Anti-Rabbit IgG H&L Alexa Fluor 594 preadsorbed
The product is subject to the following: Abcam Restricted Use Statement
Biotium Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker)(TYRP1/3283), CF647 conjugate, 0.1mg/mL
Reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium Nucleophosmin (Acute Myeloid Leukemia Marker)(NPM1/3287), CF647 conjugate, 0.1mg/mL
Recognizes a 33 kDa glycoprotein, identified as Nucleophosmin (NPM). It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugat
Biotium Napsin A (Lung Adenocarcinoma Marker)(NAPSA/3308), CF647 conjugate, 0.1mg/mL
Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium Histone H1 (Pan Nuclear Marker)(AE-4), CF647 conjugate, 0.1mg/mL
Please note that this antibody is a recombinant Rabbit version of original anti-histone H1 antibody (Clone AE-4). Because the variable heavy (VH) and variable light (VL) domains are the same, recombinant antibody has the same exact reactivity as the original AE-4 MAb. There are several advantages of producing a recombinant version of a monoclonal antibody. For example, a recombinant antibody is a pure preparation of active immunoglobulin with no contaminating non-functional intact Ig or free light/heavy chains. Secondly, antibody can always be produced, even if hybridoma line is lost. Moreover, it adds the flexibility of converting the antibody to any species, isotype or format. Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the
Biotium C1QB / Complement C1q B-Chain(C1QB/2961), CF647 conjugate, 0.1mg/mL
Complement C1q B Chain (C1qb) is a subunit of C1q. C1q is composed of 6 polypeptide chains each of C1qa, C1qb, and C1qc. C1q is a component of the classical complement pathway, and thereby plays an important role in the immune response. Each C1q subunit contains an N-terminal collagen-like region and a C-terminal C1q globular domain. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA as well as the protein. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets,
Abcam Donkey Fab'2 Anti-Mouse IgG H&L Alexa Fluor 647
Donkey Fab'2 Anti-Mouse IgG H&L Alexa Fluor 647
The product is subject to the following: Abcam Restricted Use Statement
Abcam Donkey Anti-Rabbit IgG H&L (HRP)
Donkey Anti-Rabbit IgG H&L (HRP)
The product is subject to the following: Abcam Restricted Use Statement
Abcam Donkey Anti Goat IgG H&L (Alexa Fluor 568)
Donkey Anti Goat IgG H&L (Alexa Fluor 568)
The product is subject to the following: Abcam Restricted Use Statement
Biotium Cytokeratin 8(B22.1), CF647 conjugate, 0.1mg/mL
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular (ring-like, perinuclear) from ductal (peripheral-predominant)
Abcam Donkey Anti-Sheep IgG H&L (DyLight 488).
Donkey Anti-Sheep IgG H&L (DyLight 488).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Donkey Anti Mouse IgG H&L (Alexa Fluor 568)
Donkey Anti Mouse IgG H&L (Alexa Fluor 568)
The product is subject to the following: Abcam Restricted Use Statement
Abcam Donkey Anti Sheep IgG H&L (Alexa Fluor 405)
Donkey Anti Sheep IgG H&L (Alexa Fluor 405)
The product is subject to the following: Abcam Restricted Use Statement
Abcam Donkey Anti-Mouse IgG H&L.
Donkey Anti-Mouse IgG H&L.
The product is subject to the following: Abcam Restricted Use Statement